Colon Cancer Screening Chalk Talk

1. We recommend CRC screening in average-risk individuals

between ages 50 and 75 years to reduce incidence of advanced adenoma, CRC, and mortality from CRC.

Strong recommendation; moderate-quality evidence

2. We suggest CRC screening in average-risk individuals between ages 45 and 49 years to reduce incidence of advanced adenoma, CRC, and mortality from CRC.

Conditional recommendation; very low-quality evidence

3. We suggest that a decision to continue screening beyond age 75 years be individualized.

Conditional recommendation; very low-quality evidence

4. We recommend colonoscopy and FIT as the primary screening modalities for CRC screening.

Strong recommendation; low-quality evidence

5. We suggest consideration of the following screening tests for individuals unable or unwilling to undergo colonoscopy or FIT: flexible sigmoidoscopy, multitarget stool DNA test, CT colonography or colon capsule.

Conditional recommendation; very low-quality evidence

6. We suggest against Septin 9 for CRC screening.

Conditional recommendation, very low-quality of evidence

Lynch

Amsterdam criteria

3 family members colon ovary uterus pancreas colon cancer

colon, ovary, endometrial

2 or more successive generations affected

1 family member colon cancer before age 50

FIIT q1yr -> colonoscopy

FOBT multi dna test q3yrs -> colonoscopy

CT colonography q5yrs -> colonoscopy

Flex sig q3yrs -> colonoscopy

AVM chronic disease, GAVE, Heyde's syndrome, AS, VWF, AVM, thrombocytopenia, valve replacement shearing of ADAMST13

kidney dz, diverticular painless + large volume transfusions

diverticular bleed 72 hrs

AC afib stop xarelto, allow bleed to keep going. 

warfarin keytruda clean based ulcer - fix main issue

forest classification to start anticoagulation

https://www.slideshare.net/OSUCCCJames/familial-predisposition-for-colorectal-cancers-who-to-screen