ITP vs TTP vs HUS vs DIC

 

DIC labs hb, haptoglobin, schistocytes, ldh, negative coombs test

end organ damage

pltlts 1 unit increases platelets 30K, not used in TTP/HUS, HIT

Fresh frozen plasma 2Units increase Coag by 10%, INR 1.7

Cryoprecipitate 10 Units 10 Units raise fibrinogen ~85mg/dL

hgb 1 unit hgb~1