Core Concepts
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Cardiac Output (CO) = Stroke Volume (SV) × Heart Rate (HR)
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CO reflects cardiac function and guides management of shock, fluid status, and vasopressors in critically ill patients.
Ultrasound-Based Measurement
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Only two main ultrasound measurements are needed:
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LVOT Diameter (to calculate LVOT area)
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LVOT VTI (Velocity Time Integral)
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🧠 Physiology-Based Framework
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Stroke volume is modeled as a cylinder of blood ejected through the LVOT each beat.
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SV = LVOT Area × VTI
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CO = SV × HR
🛠️ Step-by-Step Guide
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Parasternal Long Axis View:
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Identify LVOT and aortic valve.
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Measure LVOT Diameter:
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At mid-systole, near the aortic annulus; usually ~2 cm.
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Apical 5-Chamber View:
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Visualize LVOT for Doppler placement.
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Place Pulse Wave (PW) Doppler at LVOT:
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At the aortic annulus.
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Ensure Doppler angle is parallel to flow.
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Trace LVOT VTI:
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Use systolic waveform tracing; normal ~20 cm.
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Measure Heart Rate:
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Use ultrasound or patient monitor.
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Calculate Cardiac Output:
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Ultrasound machine can automate this.
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Or use formulas:
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LVOT Area = π × (Diameter ÷ 2)²
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SV = LVOT Area × VTI
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CO = SV × HR
Common Barriers for Learners
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Intimidation by math or Doppler interpretation.
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Complexity of waveform analysis.
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Fear of user error—practice improves consistency (20 scans recommended).
Tips
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Zoom for better LVOT diameter measurement.
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Ensure parallel Doppler angle to reduce error.
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Use machine’s auto-trace feature with caution—verify accuracy.
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Download PDF pocket card and use the online CO calculator for assistance.
Caveats
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Aortic valve disease (e.g., stenosis or regurgitation) can affect measurement accuracy.
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Best to measure at LVOT, not directly on stenotic aortic valve tip.
Here are POCUS-based quiz and flashcard questions based on the tutorial "Measuring Cardiac Output with Echocardiography Made Easy":
Conceptual Questions (Understanding Physiology)
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What is the formula for calculating cardiac output (CO)?
→CO = Stroke Volume × Heart Rate -
How is stroke volume (SV) estimated using echocardiography?
→SV = LVOT Area × LVOT VTI -
What anatomical structure is used to measure stroke volume in this method?
→ The Left Ventricular Outflow Tract (LVOT) -
What does LVOT VTI represent?
→ The distance blood travels through the LVOT in one heartbeat -
Why do we model stroke volume as a cylinder in this method?
→ Because blood flow through the LVOT can be approximated as a cylindrical volume.
Practical Skills Questions (Technique and Views)
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What ultrasound view is used to measure the LVOT diameter?
→ Parasternal long axis view -
At what point in the cardiac cycle should the LVOT diameter be measured?
→ At mid-systole, when the aortic valve is wide open. -
Which ultrasound view is used to place the pulse wave Doppler for VTI measurement?
→ Apical 5-chamber view -
Where exactly should the PW Doppler gate be placed to measure LVOT VTI?
→ At the aortic annulus, just below the aortic valve leaflets. -
What probe is used to perform these cardiac output measurements?
→ A phased array transducer
Interpretation and Troubleshooting
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What is a typical normal value for LVOT VTI?
→ Approximately 20 cm -
If the Doppler angle is not aligned parallel to flow, what happens to the VTI reading?
→ It will be underestimated -
How many practice scans are typically needed to reliably perform CO measurement via ultrasound?
→ About 20 scans -
Can LVOT VTI be used in aortic regurgitation?
→ Yes, but with caution due to backflow altering true stroke volume. -
Why should VTI not be measured at the tip of the aortic valve in aortic stenosis?
→ Because stenosis increases flow velocity, leading to overestimated VTI.
Calculation Questions
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How do you calculate LVOT area from its diameter?
→LVOT Area = π × (LVOT Diameter ÷ 2)² -
If LVOT diameter is 2 cm and VTI is 20 cm, what is the stroke volume?
→Area = 3.14 × (1)² = 3.14 cm²; SV = 3.14 × 20 = 62.8 mL -
If stroke volume is 60 mL and heart rate is 75 bpm, what is cardiac output?
→CO = 60 × 75 = 4500 mL/min = 4.5 L/min
Clinical Application Questions
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Why is bedside cardiac output measurement useful in shock management?
→ Helps differentiate shock types and guide fluid and vasopressor therapy -
Which patients may have unreliable CO readings using this method?
→ Those with severe aortic stenosis, arrhythmias, or poor echo window
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