TEG

on

TEG 

Citizen surgeon

https://www.youtube.com/watch?v=7PD7n5GXwNk



 1. Fibrinogen Assay: 109 mg/dL

  • Interpretation: This indicates hypofibrinogenemia, as normal fibrinogen levels typically range from 200–400 mg/dL. Low fibrinogen may contribute to a bleeding risk, as fibrinogen is a critical factor in forming a stable clot.
2. Max Amplitude (MA):
  • Max Amplitude H (MA-H KH): 49.7 mm
    • Interpretation: MA reflects clot strength and depends on both platelet function and fibrinogen. An MA of 49.7 mm is at the lower end of normal (normal range: 50-70 mm), suggesting a potential reduction in clot strength, but still within the acceptable range.
  • Max Amplitude ADP: <10 mm
    • Interpretation: This suggests severely impaired platelet function in response to ADP. A very low value (<10 mm) indicates platelet dysfunction, often seen with antiplatelet therapy (e.g., clopidogrel) or other causes of platelet inhibition.
  • Max Amplitude AA: 8.8 mm
    • Interpretation: This measures platelet response to arachidonic acid (AA) and reflects the function of the thromboxane A2 pathway. A value of 8.8 mm is very low (normal is typically >40 mm), suggesting strong inhibition of platelet function in the AA pathway, which can occur with aspirin use.
  • Max Amplitude CTF: 2.2 mm
    • Interpretation: This value is not standard, but if it reflects a clot formation measurement, a value of 2.2 mm is critically low and suggests poor clot formation ability.
3. Inhibition Percent:
  • Inhibition ADP %: 86.1%
    • Interpretation: This indicates significant inhibition of the ADP pathway, consistent with platelet inhibition, likely from medications like clopidogrel or prasugrel.
  • Inhibition AA %: 86.1%
    • Interpretation: Similarly, this suggests that the arachidonic acid (AA) pathway is heavily inhibited, commonly due to aspirin therapy.
4. Reaction Time (R Time or Tach): 11.5 minutes
  • Interpretation: Reaction time reflects the time until initial clot formation. An R-time of 11.5 minutes is mildly prolonged (normal range: 5-10 minutes), which may indicate reduced clotting factor activity or hypocoagulability.
5. Lysis at 30 Minutes (LY30 or Lysis 0): 0%
  • Interpretation: This indicates no significant clot breakdown (fibrinolysis) 30 minutes after clot formation. A normal finding, as significant lysis (>7.5%) would suggest hyperfibrinolysis and potential bleeding risk.
6. Maximum Clot Firmness (Max Clot Rapid Tach): 43.6 mm
  • Interpretation: This is another measure of overall clot strength. A value of 43.6 mm is below normal (50-70 mm), indicating reduced clot strength, likely due to the combination of platelet inhibition and reduced fibrinogen.
7. Fibrinogen Function (Fibrinogen Function Intact): 10.7 mg/dL
  • Interpretation: This reflects the functional fibrinogen contribution to clot formation. A very low value like 10.7 mg/dL confirms severe fibrinogen dysfunction or deficiency, correlating with the low fibrinogen assay (109 mg/dL).
Summary of Interpretation:
  • Platelet dysfunction: There is significant inhibition of platelet function in both the ADP and AA pathways, likely due to antiplatelet therapy (e.g., clopidogrel and aspirin).
  • Hypofibrinogenemia: Low fibrinogen levels and reduced fibrinogen function contribute to poor clot formation and reduced clot strength.
  • Clotting impairment: Overall, the patient is at increased risk for bleeding due to impaired platelet function, low fibrinogen levels, and reduced clot strength, as reflected in the low MA values and fibrinogen function.

Comments

Post a Comment